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. Author manuscript; available in PMC: 2020 Jun 28.
Published in final edited form as: Org Biomol Chem. 2019 May 30;17(24):5908–5912. doi: 10.1039/c9ob00726a

Scheme 1.

Scheme 1

Biocompatible conjugation chemistries of 2-FPBA/APBA. A) Iminoboronate formation; B) TzB/IzB complex formation of 2-FPBA; C) 2-FPBA/APBA conjugation with Tris base affording multicyclic products with much enhanced kinetic stability.