Table 1.
Trabecular Bone | BV/TV (%) |
Trabecular Thickness (μm) |
Trabecular Number (1/mm) |
Trabecular Spacing (μm) |
Connectivity Density (1/mm3) |
Structure Model Index (SMI) |
---|---|---|---|---|---|---|
WT | 12.7 ± 1.2 | 42 ± 2 | 5.40 ± 0.15 | 166 ± 6 | 164 ± 16 | 2.5 ± 0.1 |
PAR1 KO | 9.9 ± 0.9 | 40 ± 2 | 5.06 ± 0.06 | 197 ± 3 | 111 ± 8 | 2.7 ± 0.1 |
Significance | p=0.08 | NS | p<0.05 | p=0.08 | p<0.01 | NS |
N=16 bones per group |
Cortical Bone | Total Bone Length (mm) |
Cortical Bone Area (μm2) |
Cortical Porosity (%) |
Cortical Thickness (mm) |
---|---|---|---|---|
WT | 14.2 ± 0.1 | 749 ± 29 | 0.69 ± 0.09 | 0.17 ± 0.01 |
PAR1 KO | 14.3 ± 0.1 | 703 ± 28 | 0.52 ± 0.04 | 0.16 ± 0.01 |
Significance | NS | NS | NS | NS |
N=16 bones per group