Table 2.
Static Parameters | BV/TV (%) |
Number OCL/ Bone Perimeter (1/mm) |
Osteoclast Surface/Bone Surface (%) |
Osteoblast Surface/ Bone Surface (%) |
Trabecular Thickness (μm) |
Trabecular Separation (μm) |
Trabecular Number (1/mm) |
---|---|---|---|---|---|---|---|
WT | 12.0 ± 2.2 | 2.47 ± 0.71 | 5.19 ± 0.15 | 15.18 ± 2.13 | 28.96 ± 2.78 | 228.9 ± 21.8 | 4.0 ± 0.3 |
PAR1 KO | 10.4 ± 1.8 | 3.11 ± 0.36 | 5.06 ± 0.06 | 14.49 ± 2.27 | 26.97 ± 2.60 | 252.4 ± 26.7 | 3.8 ± 0.3 |
Significance | NS | NS | NS | NS | NS | NS | NS |
N=6–7 bones per group |
Dynamic Parameters | MAR μm/day |
BFR/Bone Surface μm3/μm2/day |
---|---|---|
WT | 1.97 ± 0.11 | 0.068 ± 0.010 |
PAR1 KO | 2.20 ± 0.13 | 0.092 ± 0.018 |
Significance | NS |
N=6 bones per group