Table 1.

Baseline patient characteristics and demographic data

Characteristic	All Patients (N=398)a	Malnutritiona (N=181)	No Malnutritiona (N=217)	P Value
Age (years)	65 ± 15	66 ± 15	64 ± 16	0.1
Age ≥ 65 years (N; %)	233 (59)	111 (61)	122 (56)	0.3
Male (N; %)	229 (58)	99 (55)	130 (60)	0.3
Caucasian (N; %)2	371 (97)	170 (97)	201 (97)	0.9
Weight (kg)	82 ± 25	74 ± 20	88 ± 27	<0.001
Ideal body weight (kg)	66 ± 12	62 ± 12	65 ± 11	0.05
Body mass index (kg/m2)	28 ± 8	26 ± 6	30 ± 8	<0.001
< 18.5 kg/m2	19 (5)	16 (9)	3 (1)	<0.001
Body surface area (m2)	1.9 ± 0.3	1.8 ± 0.3	2.0 ± 0.3	<0.001
APACHE III score	68 ± 21	71 ± 22	65 ± 20	0.003
SOFA score	5.2 ± 3.3	5.6 ± 3.5	4.9 ± 3.1	0.04
Charlson Comorbidity Index	5.6 ± 3.7	6.1 ± 3.5	5.3 ± 3.8	0.02
Sepsis (N; %)	267 (67)	142 (79)	125 (58)	<.001
Septic shock (N; %)	71 (18)	42 (23)	29 (13)	0.01
Invasive mechanical ventilation (N; %)	217 (55)	100 (57)	117 (54)	0.6
Renal parameters
Serum creatinine (mg/dL)	0.9 ± 0.4	0.9 ± 0.4	0.9 ± 0.3	0.2
Cystatin C (mg/L)	1.4 ± 0.6	1.5 ± 0.7	1.4 ± 0.6	0.02
Cockcroft-Gault (mL/min)	101 ± 52	95 ± 52	106 ± 51	0.03
CKD EPIcr-cysC eGFR (mL/min/1.73m2)	75 ± 30	70 ± 28	80 ± 30	<0.001
Sarcopenia Index	68.5 ± 26.2	63.9 ± 27.2	72.3 ± 24.8	0.002
Modified-NUTRIC Score	4.2 ± 1.9	4.5 ± 1.9	3.9 ± 1.9	0.004
≥ 6	96 (24)	53 (29)	43 (20)	0.03

APACHE, Acute Physiology and Chronic Health Evaluation score; CKD-EPI eGFR, Chronic Kidney Disease Epidemiology Collaborative estimated glomerular filtration rate; SOFA, Sequential Organ Failure Assessment score

^a:Values expressed as mean ± SD unless noted

^b:The modified NUTRIC score (higher score indicates greater severity of illness) is comprised of age, APACHE II, SOFA, number of co-morbidities, and days from hospital to ICU admit