Table 1.
Descriptive statistics of the study population.
| Variables (N) | GC (68) | PD (68) | APS (34) | p-value |
|---|---|---|---|---|
| Male (%) | 51.47 | 86.76 | 61.76 | 0.000a |
| Family History (%) | Nil | 16.17 | Nil | |
| Age (years), Mean ± SD | 64.76 ± 5.99 | 65.51 ± 4.71 | 67.18 ± 6.15 | 0.2159b |
| Disease duration (years) Mean ± SD | Nil | 6.11 ± 4.66 | 3.92 ± 4.13 | 0.0058c |
| BMI kg/m2, Mean ± SD | 23.14 ± 4.30 | 23.67 ± 3.18 | 24.69 ± 3.17 | 0.0919b |
| SIRT1 Mean ± SD (95% CI) ng/μL | 6.16 ± 1.13 (5.90–6.44) | 5.89 ± 0.70 (5.73–6.07) | 5.84 ± 0.90 (5.30–6.40) | OA = 0.3319b GC*PD = 0.099 GC*APS = 0.239 PD*APS = 0.961 |
| SIRT2 Mean ± SD (95% CI) ng/μL | 11.18 ± 2.35 (10.62–11.76) | 16.19 ± 2.78 (15.52–6.86) | 13.86 ± 2.56 (12.97–14.76) | OA = < 0.0001b GC*PD = p < 0.0001 GC*APS = p < 0.0001 PD*APS = p = 0.0001 |
BMI, body mass index; OA, Overall p value, GC*PD; GC vs. PD, GC*APS; GC vs. APS, PD*APS; PD vs. APS. a, chi square test; b, one-way ANOVA with Bonferroni correction; c, Wilcoxon rank sum test.