Fig. 4.

Initiation of dwarfism-like symptoms at neonatal stage of second-generation mice. a, Three-week-old mice fed LPD or NPD. Left group: male mice; right group: female mice. b, Body weight and length of 3-week-old mice at weaning. Left graph, male mice fed LPD (O) or NPD (X). Right graph, female mice fed LPD (O) or NPD (X). c, The concentration of inorganic phosphate (Pi) in milk from mice fed LPD or NPD at 14 days after parturition. Values are mean ± SD. d, The concentration of IGF-1 in 2-week-old mice fed with milk from first-generation mice fed LPD or NPD. Values are mean ± SD. e, The concentration of growth hormone in 2-week-old mice fed with milk from first-generation mice fed LPD or NPD. Values are mean ± SD. f, The serum concentration of Pi in 2-week-old mice fed with milk from first-generation mice fed LPD or NPD. Values are mean ± SD. g, Histochemical analysis of liver sections from 2-week-old mice fed with milk from first-generation mice fed LPD (right panels) or NPD (left panels). Scale bar, 10 μm. H, The serum concentration of total cholesterol in 2-week-old mice fed with milk from first-generation mice fed LPD or NPD. Values are mean ± SD.