Table 3.
Dose (TCID50/mL) | 1086 RV-A16 | RG-RV-A16 | ||||
---|---|---|---|---|---|---|
n | Mean (SD) | Median (25%–75%) | n | Mean (SD) | Median (25%–75%) | |
0 (placebo) | 9 | 3.2 (2.9) | 2 (1–5.3) | 10 | 2.0 (2.1) | 2.0 (0–3.0) |
100 | 8 | 4.6 (3.8) | 3 (2–7) | 9 | 7.2 (5.2)a | 6.0 (3.0–9.8) |
1000 | 10 | 11.4 (5.0) | 11 (9–16) | 8 | 12.3 (7.8)b | 10.5 (9.0–14) |
Abbreviations: RG, reverse genetics; RV, rhinovirus; SD, standard deviation; TCID50, median tissue culture infectious dose.
a P = .01 vs placebo.
b P = .004 vs placebo.