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. 2018 Nov 1;220(2):187–194. doi: 10.1093/infdis/jiy629

Table 3.

Peak Symptom Scores Caused by Inoculation With a Conventional Inoculum (1086) Compared With RG-RV-A16

Dose (TCID50/mL) 1086 RV-A16 RG-RV-A16
n Mean (SD) Median (25%–75%) n Mean (SD) Median (25%–75%)
0 (placebo) 9 3.2 (2.9) 2 (1–5.3) 10 2.0 (2.1) 2.0 (0–3.0)
100 8 4.6 (3.8) 3 (2–7) 9 7.2 (5.2)a 6.0 (3.0–9.8)
1000 10 11.4 (5.0) 11 (9–16) 8 12.3 (7.8)b 10.5 (9.0–14)

Abbreviations: RG, reverse genetics; RV, rhinovirus; SD, standard deviation; TCID50, median tissue culture infectious dose.

a P = .01 vs placebo.

b P = .004 vs placebo.