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. 2019 Jun 18;9:8704. doi: 10.1038/s41598-019-45056-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Representative optical microscopy images of breast cancer cells (MCF-7) not treated (NTC - red circle) and treated (TC - blue circle) with 15 nM of paclitaxel for 24 h. The rounded cell morphology observed in the TC is expected due to PTX’s action. The PTX molecule is shown in the left corner, where blue represents the carbon atoms, red represents nitrogen, cyan represents oxygen and the H atoms are shown in white.