Year	Key policy documents*	Supporting documents
1999	Appraisal of new and existing technologies: Interim guidance for manufacturers and sponsors
2001	Guide to the technology appraisal process (1st ed.) Guidance for manufacturers and sponsors/Guide to the methods of technology appraisal (1st ed.)# Guidance for appellants	Guidance for healthcare professional groups Guidance for patient/carer groups
2004	Guide to the methods of technology appraisal (2nd ed.) Guide to the technology appraisal process (2nd ed.) Technology appraisal process: guidance for appellants	A guide for manufacturers and sponsors A guide for healthcare professional groups A guide for NHS organisations A guide for patient/carer groups
2005	Social value judgements: Principles for the development of NICE guidance (1st ed.)
2006	Guide to the single technology appraisal process (1st ed.)
2007		Single Technology Appraisal Process: update
2008	Guide to the methods of technology appraisal (3rd ed.) Social value judgements: Principles for the development of NICE guidance (2nd ed.)
2009	Guide to the single technology appraisal process (2nd ed.) Guide to the multiple technology appraisal process (3rd ed.)	Supplementary advice: appraising life-extending, end-of-life treatments
2010	Appeals process guide
2011		Clarification on discounting
2013	Guide to the methods of technology appraisal (4th ed.)
2014	Guide to the processes of technology appraisal (4th ed.) Guide to the technology appraisal and highly specialised technologies appeal process
2016		Addendum A—final amendments to the NICE technology appraisal processes and methods guides to support the proposed new Cancer Drugs Fund arrangements Rapid reconsideration of drugs currently funded through the Cancer Drugs Fund
2017		Fast track appraisal: addendum to the Guide to the processes of technology appraisal Cost comparison: addendum to the Guide to the processes of technology appraisal Procedure for varying the funding requirement to take account of net budget impact
2018	Guide to the processes of technology appraisal (4th ed.)—2018 update

*Key policy documents include the methods guides, process guides, and social value judgements documents. Versions of these guides that tailor the same information for a more specialised audience (e.g. patient/carer groups, NHS organisations), plus any amendment or addendums to these key documents, have been classed as supporting documents

#The 2001 Guidance for manufacturers and sponsors document contained detailed information on the methods of technology appraisal, much of which went on to inform the development of the first formal methods guide in 2004. As such, it has been classed here as the first edition of the methods guide