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. 2019 Jun 18;9:8692. doi: 10.1038/s41598-019-45198-9

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Microbiotic composition of OF and IF samples. Microbiotic compositions at the phylum (A) and genus levels (B) were assessed by V3-V4 region 16S rRNA gene sequencing. Each bar in each category indicates each ID in consecutive order from left to right. (A) The microbiotic profiles at the phylum level are depicted in the bar graph. (B) In the heatmap, the relative abundances of the top 20 genera are displayed in yellow to red for low to high abundance, respectively. Abbreviations: precultivated neonatal oral fluid (OF), postcultivated OF in BM (BM) or YCFA (YCFA) for 48 h and infant fecal (IF) samples.