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. 2019 Jun 12;10:1248. doi: 10.3389/fmicb.2019.01248

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Copyright © 2019 Du, Xu, Yu, Liu, Zhou, Yang, Li, Chen, Zhang, Xue and Cao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Intestinal changes in newborn piglets post-challenge with E. coli of the control group and the B. subtilis strain WS-1 treatment group. (A–C) Hematoxylin and eosin (H&E)-stained intestinal tissue section (blunt intestinal villus was indicated by arrows) of a control piglet at 3 d.p.c. (D–F) H&E-stained intestinal tissue section of a B. subtilis strain WS-1 treatment piglet at 3 d.p.c. The data are representative of two independent experiments. Data are represented as mean ± SD, n = 1 or n = 2.