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. 2019 Jun 12;10:559. doi: 10.3389/fgene.2019.00559

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Copyright © 2019 Murani, Trakooljul, Hadlich, Ponsuksili and Wimmers.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Volcano plots illustrating results of pairwise comparisons of gene expression between treatments (C, saline; D10, 10 μg/kg dexamethasone; D60, 60 μg/kg dexamethasone). To visualize the extent of the overall transcriptome changes due to treatment differentially expressed genes significant at q > 0.1 showing a fold change >2 are highlighted by black dots. The red lines display the respective thresholds on corresponding log scale. Ten most significantly up- or downregulated genes, respectively, are highlighted by blue dots and annotated with corresponding gene names.