Table 1.
Maternal reported ARV exposure and feeding practice at the time of HIV PCR testing
| Birth | 6 weeks | 10 weeks | 14 weeks | ||
|---|---|---|---|---|---|
| Number of infants; n | 70 | 70 | 36 | 35 | |
| Infant body weight (kg); median (IQR) | 3.1 (2.8 to 3.3) | 4.5 (4.2 to 5.0) | 5.7 (5.2 to 6.3) | 5.9 (5.3 to 6.2) | |
| Infant prophylaxis | Daily NVP; n (%) | 69 (99%) | 64 (91%) | 12 (33%) | 3 (9%) |
| Daily NVP/AZT; n (%) | 1 (1%) | 0 | 0 | 0 | |
| None; n (%) | 0 | 0 | 24 (67%) | 24 (68%) | |
| Unknown; n (%) | 0 | 6 (9%) | 0 (0%) | 8 (23%) | |
| Infant feeding | EBF; n (%) | 68 (97%) | 53 (76%) | 29 (80%) | 24 (69%) |
| EFF; n (%) | 2 (3%) | 13 (18%) | 1 (3%) | 3 (8%) | |
| Mixed; n (%) | 0 | 4 (6%) | 0 | 0 | |
| Unknown; n (%) | 0 | 0 | 6 (17%) | 8 (23%) | |
| Mother taking cART | Yes; n (%) | 70 (100%) | 67 (96%) | 26 (72%) | 29 (74%) |
| No; n (%) | 0 | 3 (4%) | 2 (6%) | 3 (9%) | |
| Unknown; n (%) | 0 | 0 | 8 (22%) | 3 (17%) | |
| Maternal cART regimen | EFV‐based; n (%) | 66/70 (94%) | 62/67 (93%) | 25/26 (96%) | 27/29 (93%) |
| NVP‐based; n (%) | 4/70 (6%) | 5/67 (7%) | 1/26 (4%) | 2/29 (7%) | |
| Unknown; n (%) | 0 | 0 | 0 | 0 | |
| Infant EFV plasma level (ng/mL) | Median (IQR) | 1665 (1138 to 3045) | 1227 (1094 to 3015) | 1219 (909 to 1387) | 0 (0 to 0) |
| Infant NVP plasma level (ng/mL) | Median (IQR) | 3699 (2085 to 6043) | 6888 (4020 to 11549) | 3401 (2021 to 5123) | 245 (101 to 307) |
AZT, zidovudine; EBF, exclusive breastfeeding; EFF, exclusive formula feeding; EFV, efavirenz; NVP, nevirapine.