Table 1.
Control | 3 g/kg/d | 6 g/kg/d | 9 g/kg/d | P | |
---|---|---|---|---|---|
Amount ingested, g/kg/da | — | 2.8 ± 0.2b | 5.9 ± 0.2b | 8.5 ± 0.4b | <0.0004 |
Fresh mushroom, g/kg/da,c | — | 18.7 ± 1.0b | 39.5 ± 1.4b | 56.6 ± 2.7b | <0.0004 |
Calculated human dose, kg/da,d | — | 1.1 ± 0.1b | 2.4 ± 0.1b | 3.4 ± 0.2b | <0.0004 |
Corrected human dose, g/da,e | — | 91 ± 5b | 193 ± 7b | 276 ± 13b | <0.0004 |
BM change, % | –1.5 ± 0.9 | 0.7 ± 0.6b | 1.5 ± 0.4b | –1.2 ± 0.7 | 0.001 |
Water intake, ml/g BM | 1.3 ± <0.1 | 1.3 ± 0.1 | 1.2 ± 0.1 | 1.3 ± 0.1 | 0.900 |
Food intake, g/g BM | 0.7 ± <0.1 | 0.7 ± <0.1 | 0.7 ± <0.1 | 0.7 ± <0.1 | 0.569 |
Liver mass/BM, % | 5.14 ± 0.16 | 6.35 ± 0.83b | 5.03 ± 0.99 | 5.08 ± 0.09 | 0.047 |
Kidneys mass/BM, % | 1.86 ± 0.07 | 2.01 ± 0.16 | 1.88 ± 0.04 | 1.88 ± 0.06 | 0.576 |
Spleen mass/BM, % | 0.44 ± 0.03 | 0.44 ± 0.06 | 0.38 ± 0.04 | 0.41 ± 0.03 | 0.769 |
Adrenals mass/BM, ‰ | 0.16 ± 0.02 | 0.16 ± 0.02 | 0.17 ± 0.03 | 0.14 ± 0.01 | 0.759 |
Testes mass/BM, % | 0.47 ± 0.02 | 0.42 ± 0.05 | 0.48 ± 0.03 | 0.47 ± 0.03 | 0.429 |
BM: body mass.
All dose groups differ significantly from each other (generalized linear model, P < 0.05).
Differs significantly from the controls (generalized linear model, P < 0.05).
The calculated dose of fresh mushroom.
The calculated dose of fresh mushroom for a 60-kg person.
The calculated dose of fresh mushroom for a 60-kg person normalized to body surface area.25