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. 2019 Jun 18;69(684):e470–e478. doi: 10.3399/bjgp19X704321

Table 4.

Cascade effects of testing in 6-month period after testing

Mean number of GP appointments per persona (95% CI) Mean number of phlebotomy appointments in 6 months (95% CI) Mean number of total tests requested (95% CI) Mean number of referrals per person (95% CI)
True-positives, n= 5712 15.0b (14.7 to 15.3) 4.26b (4.15 to 4.37) 43.7b (42.3 to 45.2) 0.86b (0.83 to 0.89)
False-negatives, n= 5912 12.0b (11.7 to 12.2) 3.23b (3.14 to 3.32) 30.0b (28.8 to 31.2) 0.78b (0.75 to 0.81)
False-positives, n= 32 298 10.3b (10.2 to 10.4) 2.78b (2.75 to 2.82) 24.3b (23.9 to 24.7) 0.62b (0.61 to 0.64)
True-negatives, n= 93 039 7.29b (7.2 to 7.3) 1.81b (1.80 to 1.83) 13.7b (13.5 to 13.8) 0.52b (0.51 to 0.52)
Untested controls n= 37 539 4.80 (4.74 to 4.86) 1.14 (1.12 to 1.16) 9.66 (9.47 to 9.85) 0.24 (0.24 to 0.25)

True-positives = people with a positive test who develop relevant disease. False-negatives = people with a negative test who develop relevant disease. False-positives = people with a positive test with no relevant disease. True-negatives = people with a negative test with no relevant disease.

a

Includes face-to-face consultations, home visits, and telephone consultations.

b

P<0.001 — comparing true-positives to false-negatives and comparing false-positives to true-negatives.