Table 1. . Summary of patient demographics.
Demographic | Number | |
---|---|---|
Age, median (months) | 67 ± 14.3 | |
Duration of follow-up, median (months) | 7 (1–55) | |
Gender: | Male | 38 (74.5%) |
Female | 13 (25.5%) | |
Performance status: | 0 | 30 (58.8%) |
1 | 19 (37.2%) | |
2 | 2 (4.0%) | |
Cancer type: | Cutaneous melanoma | 46 (90.2%) |
Ocular melanoma | 5 (9.8%) | |
Primary cancer resected prior to therapy: | Yes | 43 (84.3%) |
No | 8 (15.7%) | |
Number of systemic treatments prior to therapy: | 0 | 44 (86.3%) |
1 | 7 (13.7%) | |
BRAF mutation status: | Wild-type | 36 (70.6%) |
Positive | 6 (11.8%) | |
Unknown | 9 (17.6%) | |
Nature of prior treatment: | Immunotherapy | 3 |
Chemotherapy | 4 | |
Type of immunotherapy: | Ipilimumab | 16 (31.4%) |
Nivolumab | 2 (3.9%) | |
Pembrolizumab | 33 (64.7%) | |
Mean number of cycles of immunotherapy: | Ipilimumab | 3.5 (2–4) |
Nivolumab | 3.5 (3–4) | |
Pembrolizumab | 14.7 (1–50) | |
Presence of hypophysitis: | Yes | 6 (11.7%) |
No | 45 (88.3%) |