Table 3. . Immune-mediated adverse events.

Case	Immunotherapy	Immune-mediated adverse effect	Grade
1	Pembrolizumab	Dermatitis in lips	1
2	Pembrolizumab	Rash	1
3	Pembrolizumab	Rash	1
4	Pembrolizumab	Hypothyroidism	1
5	Pembrolizumab	Hypothyroidism	2
6	Pembrolizumab	Hypothyroidism	2
7	Pembrolizumab	Thrombocytopenia	3
8	Pembrolizumab	Hypophysitis	3
9	Ipilimumab	Hypophysitis	1
10	Ipilimumab	Rash	1
11	Ipilimumab	Colitis	2
12	Ipilimumab	Hypophysitis	2
13	Ipilimumab	Hypophysitis	3
14	Ipilimumab	Hypophysitis	3
15	Ipilimumab	Hypophysitis	3