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. 2019 Jun 18;50:46. doi: 10.1186/s13567-019-0663-x

Table 5.

Proteins of which the normalized abundance in ileal content was significantly different between control and challenged groups

Accession number Protein name Abbreviation p-value Highest mean
O57579 Aminopeptidase Ey AMPN 0.0012 Control
Q10751 Angiotensin-converting enzyme ACE 0.0006 Control
P08250 Apolipoprotein A-1 APOA1 0.0364 Challenge
P00508 Aspartate aminotransferase, mitochondrial AATM 0.0067 Control
Q05744 Cathepsin D CATD 0.0203 Control
P02263 Histone H2A-IV H2A4 0.0079 Challenge
P20763 Ig lambda chain C region LAC 0.0155 Control
P04210 Ig lambda chain V-1 region LV1 0.0370 Control
P41263 Retinol-binding protein 4 RET4 0.0399 Challenge
P80566 Superoxide dismutase [Cu–Zn] SOD 0.0004 Control
P27731 Transthyretin TTR 0.0091 Control
O93277 WD repeat-containing protein 1 WDR1 0.0027 Control

Proteomics using high performance liquid chromatography–mass spectrometry (HPLC–MS) was performed on ileal content of animals from the control (n = 9) and challenge (n = 9) group at day 26. This resulted in 3 proteins with a significantly higher normalized abundance (p < 0.05) and 9 proteins with a significantly lower normalized abundance (p < 0.05) in challenged birds.