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. 2019 Jun 19;20:15. doi: 10.1186/s12860-019-0197-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Effects of recombinant SAA1 protein treatment for different time points on NOX4/ROS pathway in LPS-induced VSMCs (n = 3). Notes: The levels of O₂⁻ production (a), NADPH oxidase activity (b) and NOX-4 protein (c-d) in VSMC after pre-incubation with 20 μg/ml SAA1 for different time points (0, 24, 48, 72 h) followed by the addition with 1 μg/ml LPS for 24 h. The same letters represented no significant differences, P > 0.05; and different letters indicated significant differences, P < 0.05