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. 2019 Jun 18;10:180. doi: 10.1186/s13287-019-1285-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Bone formation in irradiated bone defects and the expression of miR-34a in newly formed bone. a, b Micro-CT and H&E images of bone formation in bone defects of non-irradiated (0 Gy) and irradiated (15 Gy) rats 2, 4, and 8 weeks after surgery; scale bar of CT 2D images = 1.5 mm; scale bar of H&E images = 1 mm. d BV/TV in the cortical bone area. c BV/TV in the trabecular bone area. d Expression of miR-34a in the newly formed bone of non-irradiated (N-BD) or irradiated (IR-BD) rats. Data are shown as mean ± SD, n = 3; *p < 0.05. **p < 0.01, ***p < 0.001