Table 1.
Descriptive statistics for this sample. Age, Education, and Years lived with depression are measured in years (W=Wilcoxon’s rank sum). Years lived with depression was defined as current age minus age of first lifetime episode of major depression. Median and interquartile range (IQR) is reported when Wilcoxon’s rank sum test is done. Frequencies are reported when using Fisher’s exact p. MMSE – Mini-mental state examination; MADRS – Montgomery-Asberg Depression Rating Scale, MMSE – Mini-mental state examination.
| Responders [N=15] | Non-Responders [N=11] | W, Fisher’s Exact Test | p-value | |
|---|---|---|---|---|
| Age | 65 (5) | 67 (5) | W=185 | 0.349 |
| Sex (F) | 13 | 8 | Fisher’s exact p | 0.62 |
| Race (CC/AA) | 11/4 | 11/0 | Fisher’s exact p | 0.113 |
| Education | 15 (3) | 15 (2) | W=200 | 0.916 |
| Years lived with Depression | 29 (20) [N=11] | 33 (17) | W=123 | 0.818 |
| (Single/Recurrent) Depression | 2/11 [N=13] | 4/7 | Fisher’s exact p | 0.357 |
| MMSE | 29 (1) | 28 (1) | W=118 | 0.094 |
| Baseline MADRS | 26 (7) | 29 (5) | W=179 | 0.222 |
| End of trial MADRS | 7 (8) | 16 (7) | W=118 | 0.010* |
| End of trial Venla | 144 (121) [N=11] | 181 (110) [N=7] | W=16 | 0.433 |
| End of trial Desvenla | 253 (118) [N=11] | 405 (152) [N=7] | W=10.5 | 0.133 |
| Baseline Coding (Processing Speed) | 10.3 (5.9) | 8.7 (3.8) | W=218 | 0.2832 |
| Baseline List Recall (Delayed Verbal Memory) | 10.0 (3.3) | 11.4 (2.7) | W=188 | 0.4589 |
| Baseline Story Recall (Delayed Verbal Memory) | 10.3 (5.2) | 10.3 (2.9) | W=190 | 0.5575 |
| Baseline Figure Recall (Delayed Visuospatial Memory) | 8.9 (5.1) | 8.8 (3.0) | W=205 | 0.7821 |
| Baseline Trail Making (Set Shifting) | 10 (4.5) | 10.5 (1.5) | W=187 | 0.4382 |
| Baseline Color-Word Interference-Inhibition (Response Inhibition) | 10.3 (5.0) | 12.0 (4.5) | W=185 | 0.367 |
| Baseline Color-Word Interference-Inhibition/Switching (Response Inhibition and Switching) | 9.0 (4.5) | 10.0 (1.5) | W=191 | 0.5998 |