Table 2.

Hazard ratios for meningioma among patients with breast cancer with and without using tamoxifen as revealed by the time-dependent regression model.

	Breast cancer without using tamoxifen	Breast cancer with using tamoxifen
No. of meningioma	35	42
Person-years	116,553	237,572
Incidence rates (per 10,000 person-years)	3.00	1.77
Crude HR (95% CI)	1.00	0.59 (0.38, 0.93)*
Adjusted HR (95% CI)#	1.00	0.64 (0.40, 1.02)

CI, confidence interval; HR, hazard ratio ^#Adjusted for age, comorbidity, steroid use, statin use, thiazide diuretics use, treatment I, and treatment II. *P < 0.05.