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. 2019 Feb 16;105(12):911–919. doi: 10.1136/heartjnl-2018-314482

Table 3.

Clinical and echocardiographic data of studies without valvular outflow obstruction according to AVA > or ≤ 1.5 cm2

AVA >1.5 cm2 AVA ≤1.5 cm2 P value
Patients, n 11 980 710
Studies, n 13 774 856
Aortic valve type, n (%) <0.001
 Normal 7932 (58) 256 (30)
 Sclerosis 5842 (42) 600 (70)
Age, years 65±19 76±17 <0.001
Sex male, n (%) 6422 (54) 188 (27) <0.001
Body surface area, m2 1.79±0.21 1.63±0.18 <0.001
Peak aortic jet velocity, cm/s 139±32 169±34 <0.001
Stroke volume (mL) 71±21 41±11 <0.001
Aortic time–velocity integral, cm 29±7 34±9 <0.001
LVOT diameter, cm 2.1±0.2 1.9±0.2 <0.001
LVOT time–velocity integral, cm 21±5 18±5 <0.001
LV end diastolic volume, mL 114±50 126±57 0.02
LV end systolic volume, mL 59±41 76±51 <0.001
LV ejection fraction, % 58±10 54±12 <0.001
LV mass index, g/m2 85±27 91±29 0.02
Relative wall thickness 0.4±0.1 0.5±0.2 0.18
Mitral regurgitation, n (%) <0.001
 0–I 8715 (63) 425 (50)
 II 3733 (27) 219 (26)
 III 1055 (8) 142 (17)
 IV 271 (2) 70 (8)

Data presented as mean±SD, except otherwise indicated.

AVA, aortic valve area; LVOT, left ventricular outflow tract.