Table 3.
Variable | Number of SMD included | Subgroups | Pooled effect estimate | 95% CI | I 2 (%) | Overall I 2 (%) | |
---|---|---|---|---|---|---|---|
BMI | Dosage of curcumin (mg/day) | 4 | ≤500 (mg/day) | −0.46 | −0.93, 0.01 | 79.2 | 69.7 |
10 | >500 (mg/day) | −0.33 | −0.63, −0.03 | 68.2 | |||
Duration of study (week) | 10 | ≤8 weeks | −0.42 | −0.69, −0.14 | 72.1 | ||
4 | >8 weeks | −0.24 | −0.79, 0.32 | 71.1 | |||
Body weight | Dosage of curcumin (mg/day) | 5 | ≤500 (mg/day) | −0.43 | −0.85, −0.00 | 78.1 | 45.7 |
10 | >500 (mg/day) | −0.19 | −0.33, −0.04 | 0.0 | |||
Duration of study (week) | 11 | ≤8 weeks | −0.25 | −0.46, − 0.04 | 54.9 | ||
4 | >8 weeks | −0.22 | −0.47, 0.03 | 52.4 | |||
WC | Dosage of curcumin (mg/day) | 2 | ≤500 (mg/day) | 0.07 | −0.33, 0.46 | 0.0 | 42.1 |
7 | >500 (mg/day) | −0.31 | −0.51, −0.10 | 41.4 | |||
Duration of study (week) | 5 | ≤8 weeks | −0.15 | −0.36, 0.07 | 5.1 | ||
4 | >8 weeks | −0.34 | −0.64, −0.04 | 51.6 | |||
HR | Dosage of curcumin (mg/day) | 1 | ≤500 (mg/day) | 0.11 | −0.68, 0.90 | - | 0.0 |
4 | >500 (mg/day) | −0.20 | −0.46, 0.06 | 0.0 | |||
Duration of study (week) | 3 | ≤8 weeks | −0.23 | −0.51, 0.06 | 0.0 | ||
2 | >8 weeks | 0.02 | −0.49, 0.53 | 0.0 | |||
Leptin | Dosage of curcumin (mg/day) | 2 | ≤500 (mg/day) | −0.86 | −1.42, −0.30 | 6.0 | 0.0 |
2 | >500 (mg/day) | −0.99 | −1.22, −0.75 | 0.0 | |||
Duration of study (week) | 3 | ≤8 weeks | −0.86 | −1.19, −0.53 | 0.0 | ||
1 | >8 weeks | −1.05 | −1.34, −0.76 | - | |||
Adiponectin | Dosage of curcumin (mg/day) | 2 | ≤500 (mg/day) | 0.65 | −0.11, 1.41 | 50.4 | 94.5 |
3 | >500 (mg/day) | 1.28 | 0.15, 2.41 | 97.1 | |||
Duration of study (week) | 3 | ≤8 weeks | 0.95 | 0.27, 1.63 | 70.3 | ||
2 | >8 weeks | 1.23 | −0.49, 2.94 | 98.5 |