Table 3.
Fully adjusted multivariate regression model from analysis of the relationship between PA in total MET-min/week and maximal NC/C ratio (p values less than 0.05 are in bold)
| Covariate | Effect estimate | SE | 95% CI | P value | |
| Low | High | ||||
| Age (per SD: 7.68 years) | 0.041 | 0.015 | 0.000 | 0.077 | 0.031 |
| Sex (male) | −0.169 | 0.050 | −0.267 | −0.071 | 0.001 |
| Ethnicity (Caucasian) | 0.210 | 0.182 | −0.148 | 0.568 | 0.249 |
| Height (per SD: 9.26 cm) | −0.009 | 0.028 | −0.065 | 0.037 | 0.610 |
| BMI (per SD: 4.19 kg/m2) | −0.034 | 0.017 | −0.071 | 0.000 | 0.054 |
| SBP (per SD: 18.0 mm Hg) | −0.018 | 0.018 | −0.072 | 0.018 | 0.344 |
| DBP (per SD: 9.64 mm Hg) | −0.010 | 0.019 | −0.058 | 0.029 | 0.640 |
| HR (per SD: 11.7 bpm) | 0.012 | 0.012 | −0.023 | 0.047 | 0.476 |
| Average household income before tax: | |||||
| Less than £18 000 | 0.014 | 0.053 | −0.089 | 0.117 | 0.788 |
| £31 000–£51 999 | −0.053 | 0.041 | −0.134 | 0.027 | 0.192 |
| £52 000–£100 000 | −0.067 | 0.049 | −0.163 | 0.029 | 0.170 |
| Greater than £100 000 | −0.005 | 0.073 | −0.147 | 0.138 | 0.946 |
| Degree level or professional education | −0.041 | 0.032 | −0.105 | 0.022 | 0.204 |
| Townsend deprivation index (per SD: 2.68) | −0.021 | 0.016 | −0.054 | 0.011 | 0.178 |
| Smoking status: | |||||
| Never smoked | −0.028 | 0.078 | −0.181 | 0.125 | 0.718 |
| Previous smoker | −0.052 | 0.079 | −0.208 | 0.103 | 0.509 |
| Regular alcohol use | −0.021 | 0.032 | −0.083 | 0.042 | 0.519 |
| Diabetes mellitus | −0.082 | 0.070 | −0.220 | 0.055 | 0.240 |
| Cardiovascular disease | −0.014 | 0.058 | −0.127 | 0.100 | 0.811 |
| Hypertension | −0.084 | 0.057 | −0.196 | 0.027 | 0.138 |
| Antihypertensive use | 0.017 | 0.064 | −0.108 | 0.142 | 0.790 |
| Statin use | 0.002 | 0.044 | −0.084 | 0.089 | 0.956 |
| LVEDV (per SD: 33.3 mL/m2) | 0.166 | 0.025 | 0.112 | 0.210 | <0.001 |
| LV mass (per SD: 24.1 g/m2) | −0.120 | 0.028 | −0.174 | −0.065 | <0.001 |
| LVEF (per SD: 5.91%) | −0.033 | 0.016 | −0.064 | −0.016 | 0.039 |
| Total MET-min/week (per IQR: 3505 MET-min/week) | −0.001 | 0.019 | −0.039 | 0.037 | 0.966 |
BMI, body mass index; DBP, diastolic blood pressure; LV, left ventricular; LVEDV, LV end-diastolic volume; LVEF, LV ejection fraction; MET, metabolic equivalent of task; NC/C, non-compaction/compaction; PA, physical activity; SBP, systolic blood pressure.