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TP53-mutated breast cancers (BCs) have more elevated expression of HLA genes than TP53-wildtype BCs. (a) Heatmap shows that TP53-mutated BCs likely more highly express HLA genes than TP53-wildtype BCs (METABRIC). (b) HLA genes are more frequently amplified in TP53-mutated BCs than in TP53-wildtype BCs. The length of the bars in the rose diagram is proportional to the frequency of HLA gene amplification in TP53-mutated or TP53-wildtype BCs.
