Table 5.
Multivariate analysis of prognostic variables in 204 colorectal cancer patients (p-value was performed using Cox proportional hazard model).
| Characteristic | N=204 | β | Hazard ratio | 95% CI | p-value |
|---|---|---|---|---|---|
| Distant metastasis | 2.718 | 15.151 | 6.502-35.303 | <0.001 | |
| No | 185 | ||||
| Yes | 19 | ||||
| TNM stage | 1.434 | 4.195 | 1.869-9.415 | 0.001 | |
| I/II | 106 | ||||
| III/IV | 98 | ||||
| PD-L1 | 0.649 | 1.914 | 1.031-3.553 | 0.040 | |
| Negative | 120 | ||||
| Positive | 84 | ||||
| A2aR | 0.875 | 2.400 | 1.264-4.558 | 0.007 | |
| Negative | 96 | ||||
| Positive | 108 |
Notes: potential prognostic factors were selected based on univariate results (p<0.05) to conduct multivariate analysis using Cox proportional hazards regression models. Positive PD-L1 status (HR=1.914, 95% CI:1.031-3.553, p=0.040), positive A2aR expression (HR=2.400, 95% CI: 1.264-4.558, p=0.007), distant metastasis (HR=15.151, 95% CI: 6.502-35.303, p<0.001), and TNM stage (HR=4.195, 95% CI: 1.869-9.415, p=0.001) could be independent prognostic predictors for colorectal cancer patients.