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. Author manuscript; available in PMC: 2019 Jun 19.
Published in final edited form as: J Mammary Gland Biol Neoplasia. 2018 Aug 9;23(4):249–267. doi: 10.1007/s10911-018-9407-1

Fig 7. Stromal derived CXCL1 promotes 144epi cell invasion through CXCR2 dependent mechanisms.

Fig 7.

A-B. P-CAFs were transfected with control (Ctrl) or CXCL1 siRNAs, analyzed for CXCL1 expression by ELISA (A) and 144epi cell invasion by Matrigel transwell assay (B). C. Control (Ctrl) or CXCR2 shRNA expressing144epi cells (G-1, F-6) were co-cultured with control or CXCL1 siRNA transfected P-CAFs and analyzed for changes in invasion by Matrigel transwell assay. Statistical analysis was determined by One Way ANOVA followed by Bonferroni post-hoc analysis. Triplicate samples per group were plated; experiments were performed three times. Statistical significance was determined by p <0.05. *p<0.05; **p<0.01, ns=not significant. Mean±SEM are shown.