. Author manuscript; available in PMC: 2020 Jun 14.

Published in final edited form as: Circ Cardiovasc Imaging. 2019 Jun 14;12(6):e009228. doi: 10.1161/CIRCIMAGING.119.009228

Table 2.

Multivariable linear regression models for the association of log-transformed CAC score and LV structure and function at Y25

	Univariate Analysis			Multivariable Analysis^*
	Coefficient	SE	Adjusted p- values^†	Coefficient	SE	Adjusted p-values^†
LV Mass Index (g/m²)	2.408	0.206	<0.001	1.218	0.213	0.007
LV End-Diastolic Volume (mL)	2.784	0.282	<0.001	0.811	0.265	0.007
LV End-Systolic Volume (mL)	1.302	0.169	<0.001	0.350	0.165	0.048
LV Ejection Fraction (%)	−0.126	0.070	0.071	−0.029	0.078	0.834
LV Longitudinal Strain (%)	0.111	0.024	<0.001	0.005	0.025	0.836
LA Volume Index (mLm²)	0.089	0.021	<0.001	0.214	0.074	0.009
E/e' Ratio	0.193	0.047	<0.001	0.059	0.022	0.014

Adjusted for year-25 covariates: age, sex, race, educational years, body mass index, systolic blood pressure, use of anti-hypertensive medication, total cholesterol, HDL-cholesterol, use of lipid-lowering medication, diabetes mellitus, smoking status, alcohol consumption, and physical activity.

^†

P-values adjusted for multiple comparisons using the Benjamini-Hochberg procedure.

CAC = coronary artery calcium; LA = left atrial LV = left ventricular; SE = standard error; Y25 = year-25 examination.