Table 5.
Associations of PM10a and COb with serum and cervico-vaginal inflammatory markers in 104 pregnant women, Mexico City, PRINCESA Cohort, 2009–2014.
| TNFα | IL-6 | IP-10 | MIP-1α | MIP-1β | MCP-1 | Eotaxin | |||
|---|---|---|---|---|---|---|---|---|---|
| CVE (Betas (SEe)) | |||||||||
| Overall SDf | 2.15 | 2.38 | 1.78 | 2.48 | 1.96 | 2.22 | 2.02 | ||
| PM10 c | −0.22 (0.12)c | −0.22 (0.15) | −0.25 (0.10)c | −0.18 (0.13) | −0.21 (0.11)c | −0.26 (0.12)c | −0.29 (0.13)c | ||
| CO | −0.54 (0.31)c | −0.79 (0.42)c | −0.2 0 (0.29) | −0.50 (0.40) | −0.60 (0.28)c | −1.01 (0.31)d | −0.62 (0.30)c | ||
| Serum (Beta and (SE)) | |||||||||
| Overall SD | 1.12 | 1.7 | 0.71 | 1.72 | 0.92 | 0.59 | 1.02 | ||
| PM10 | 0.05 (0.05) | 0.19 (0.09)c | 0.09 (0.03)d | 0.07 (0.06) | 0.07 (0.03)c | 0.02 (0.02) | 0.09 (0.05)c | ||
| CO | −0.01 (0.12) | 0.01 (0.27) | 0.13 (0.10) | −0.14 (0.18) | −0.16 (0.09)c | −0.02 (0.07) | 0.08 (0.16) | ||
Note: Units for pollutants: PM10 (per 10 μg/m3); CO (per 10 ppm). Results are from Tobit regression models, which used air pollution data (1 day prior to clinic visit) from the monitor nearest each participant’s residence and adjusted for pre-pregnancy body mass index, gestational age at the time of sampling (weeks), education, maximum temperature for the day prior to visit and season.
a
PM10, particulate matter with an aerodynamic diameter 10 μm or less
b
CO, carbon monoxide
c
p ≤ 0.1 after adjusting for False Discovery Rate (FDR)
d
p ≤ 0.05 after adjusting for FDR
e
SE, standard error
f
SD, standard deviation