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. Author manuscript; available in PMC: 2019 Dec 11.
Published in final edited form as: Anal Chim Acta. 2018 Mar 9;1037:256–264. doi: 10.1016/j.aca.2018.02.051

Table 1.

Exosomal lipid-based classification of normal versus early and late stage NSCLC using Random Forest and LASSO.

Subjects AUROC Std 95% CI Sensitivity Std 95%CI Specificity Std 95% CI
Random Forest (with top 16 features)

Normal vs_Early 0.85 0.09 0.62 0.99 0.77 0.16 0.43 1.00 0.72 0.17 0.38 1.00
Normal vs Late 0.88 0.08 0.69 1.00 0.84 0.12 0.57 1.00 0.72 0.16 0.42 1.00
Early vs Late 0.64 0.12 0.41 0.84 0.67 0.16 0.31 1.00 0.54 0.17 0.22 0.89

LASSO

Normal vs_Early 0.79 0.04 0.71 0.85 0.65 0.09 0.46 0.78 0.77 0.05 0.66 0.85
Normal vs Late 0.77 0.04 0.68 0.83 0.54 0.08 0.37 0.70 0.82 0.04 0.73 0.89
Early vs Late 0.51 0.05 0.41 0.61 0.33 0.09 0.16 0.51 0.73 0.09 0.53 0.90