Table 3. Differences in Postoperative Outcomes Between Non–Screen-Detected and Screen-Detected Colorectal Cancera.
| Operation Year 2014-2016 | No. (%) | Absolute Risk Reduction, % (95% CI) | Univariable vs Multivariableb | Screen Detected vs Not Screen Detected Odds Ratio (95% CI) | |
|---|---|---|---|---|---|
| Screen Detected | Not Screen Detected | ||||
| Colonc,d | |||||
| Total No. | 4696 | 15 936 | NA | NA | NA |
| Nonsurgical postoperative complication | 555 (11.8) | 2941 (18.5) | 6.7 (5.6-7.8) | Univariable | 0.59 (0.54-0.65)e |
| Multivariable | 0.81 (0.73-0.91)e | ||||
| Surgical postoperative complication | 563 (12.0) | 2714 (17.0) | 5.0 (3.9-6.1) | Univariable | 0.66 (0.60-0.73)e |
| Multivariable | 0.80 (0.72-0.89)e | ||||
| Complicated course | 434 (9.2) | 2293 (14.4) | 5.2 (4.2-6.2) | Univariable | 0.61 (0.54-0.68)e |
| Multivariable | 0.80 (0.71-0.90)e | ||||
| Mortality | 30 (0.6) | 295 (1.9) | 1.3 (1.0-1.6) | Univariable | 0.34 (0.23-0.50)e |
| Multivariable | 0.74 (0.49-1.12) | ||||
| Rectumc,f | |||||
| Total No. | 1582 | 7936 | NA | NA | NA |
| Nonsurgical postoperative complication | 293 (18.5) | 1733 (21.8) | 3.3 (1.1-5.4) | Univariable | 0.81 (0.71-0.93)e |
| Multivariable | 0.99 (0.85-1.15) | ||||
| Surgical postoperative complication | 323 (20.4) | 1837 (23.1) | 2.7 (0.4-4.8) | Univariable | 0.85 (0.75-0.97)e |
| Multivariable | 0.99 (0.86-1.15) | ||||
| Complicated course | 266 (17.2) | 1511 (19.2) | 2.0 (−0.1 to 4.0) | Univariable | 0.93 (0.80-1.07) |
| Multivariable | 1.03 (0.88-1.21) | ||||
| Mortality | 19 (1.2) | 81 (1.0) | −0.2 (−0.9 to 0.2) | Univariable | 1.27 (0.79-2.06) |
| Multivariable | 2.27 (1.31-3.96)e | ||||
Abbreviation: NA, not applicable.
Univariable and multivariable analysis for the odds on different preoperative and postoperative outcomes for 2014 to 2016 for screen-detected vs non–screen-detected patients undergoing surgery for primary colorectal cancer.
Frequency of missing values in multivariable analysis colon: 49 (0.2%) (missing: sex, n = 10; age, n = 12; American Society of Anesthesiologists score, n = 7; previous abdominal surgery, n = 21). Frequency of missing values rectum: 191 (2%) (missing: sex, n = 8; age, n = 8; American Society of Anesthesiologists score, n = 2; tumor distance from anal verge, n = 167).
The following factors were included in the multivariable model to correct for differences in case mix between patients: age, sex, body mass index, American Society of Anesthesiologists score, Charlson comorbidity score, any tumor-related complication, previous abdominal surgery, pathologic tumor classification, presence of metastasis, additional resection due to tumor invasion, and additional resection due to metastasis.
Added for the colon: location of tumor within colon.
Significant values.
Added for the rectum: received radiotherapy (no short-course radiotherapy with immediate surgery, short-course radiotherapy with delayed surgery, or chemoradiation/long-course radiotherapy), procedure (lower anterior resection, abdominal perineal resection, or different), clinical tumor classification, and tumor distance from anal verge.