Table 2. Positive Margin Rate by Demographic and Clinical Characteristics of Patients.
| Positive Margin Rate, No. (%) | Risk Ratio (95% CI) | |
|---|---|---|
| Age, y | ||
| <65 | 5249 (18.2) | 1 [Reference] |
| ≥65 | 4759 (16.5) | 0.91 (0.86-0.96) |
| Sex | ||
| Male | 5508 (19.1) | 1 [Reference] |
| Female | 4066 (14.1) | 0.74 (0.70-0.78) |
| Race/ethnicity | ||
| White | 5047 (17.5) | 1 [Reference] |
| Black | 5595 (19.4) | 1.11 (1.01-1.21) |
| Hispanic | 4960 (17.2) | 0.98 (0.86-1.11) |
| Asian or Pacific Islander | 4038 (14.0) | 0.80 (0.66-0.96) |
| Other or unknown | 4730 (16.4) | 0.93 (0.76-1.15) |
| Insurance status | ||
| Private | 5105 (17.7) | 1 [Reference] |
| Medicare or other government insurance | 4932 (17.1) | 0.97 (0.92-1.02) |
| Medicaid | 5537 (19.2) | 1.09 (1.00-1.19) |
| Unknown or uninsured | 4932 (17.1) | 0.97 (0.87-1.08) |
| Socioeconomic status | ||
| Low | 5047 (17.5) | 1 [Reference] |
| Middle | 5220 (18.1) | 1.04 (0.98-1.10) |
| High | 4932 (17.1) | 0.98 (0.92-1.04) |
| Unknown | 4441 (15.4) | 0.88 (0.58-1.34) |
| Comorbidity index | ||
| 0 | 5018 (17.4) | 1 [Reference] |
| 1 | 5162 (17.9) | 1.03 (0.97-1.10) |
| ≥2 | 5249 (18.2) | 1.04 (0.94-1.16) |
| Primary site | ||
| Oral cavity | 3115 (10.8) | 1 [Reference] |
| Oropharynx | 8508 (29.5) | 2.74 (2.58-2.90) |
| Hypopharynx | 7787 (27.0) | 2.51 (2.13-2.94) |
| Larynx | 5681 (19.7) | 1.83 (1.70-1.96) |
| Tumor grade | ||
| 1 | 2682 (9.3) | 1 [Reference] |
| 2 | 4960 (17.2) | 1.84 (1.68-2.03) |
| 3 | 7181 (24.9) | 2.68 (2.43-2.95) |
| Unknown | 4816 (16.7) | 1.79 (1.58-2.03) |
| Pathologic T category | ||
| 1 | 3201 (11.1) | 1 [Reference] |
| 2 | 5480 (19.0) | 1.71 (1.59-1.83) |
| 3 | 5797 (20.1) | 1.81 (1.65-1.98) |
| 4 | 5681 (19.7) | 1.77 (1.64-1.92) |
| X | 9690 (33.6) | 3.03 (2.82-3.25) |
| Pathologic N category | ||
| 0 | 2596 (9.0) | 1 [Reference] |
| 1 | 4960 (17.2) | 1.92 (1.74-2.11) |
| 2 | 6201 (21.5) | 2.39 (2.22-2.58) |
| 3 | 8018 (27.8) | 3.09 (2.54-3.76) |
| X | 7239 (25.1) | 2.79 (2.60-3.00) |
| Clinical TNM stage | ||
| I | 2653 (9.2) | 1 [Reference] |
| II | 4816 (16.7) | 1.81 (1.66-1.98) |
| III | 6345 (22.0) | 2.39 (2.20-2.60) |
| IVA | 6922 (24.0) | 2.61 (2.43-2.81) |
| IVB | 10 296 (35.7) | 3.88 (3.25-4.62) |
| Facility volume | ||
| Low (<25th percentile) | 7585 (26.3) | 1 [Reference] |
| Medium (25th-75th percentile) | 4759 (16.5) | 0.63 (0.59-0.66) |
| High (>75th percentile) | 3115 (10.8) | 0.41 (0.38-0.44) |
| Facility type | ||
| Nonacademic | ||
| CCP | 8133 (28.2) | 1 [Reference] |
| CCCP | 6576 (22.8) | 0.81 (0.74-0.89) |
| INCP | 5566 (19.3) | 0.68 (0.61-0.76) |
| Academic | 4038 (14.0) | 0.50 (0.45-0.54) |
| Facility location | ||
| New England | 6489 (22.5) | 1 [Reference] |
| Middle Atlantic | 4124 (14.3) | 0.63 (0.56-0.72) |
| South Atlantic | 5451 (18.9) | 0.84 (0.75-0.94) |
| East North Central | 4845 (16.8) | 0.75 (0.67-0.84) |
| East South Central | 4816 (16.7) | 0.74 (0.65-0.85) |
| West North Central | 4701 (16.3) | 0.72 (0.63-0.82) |
| West South Central | 4845 (16.8) | 0.75 (0.65-0.86) |
| Mountain | 5797 (20.1) | 0.89 (0.77-1.03) |
| Pacific | 5739 (19.9) | 0.89 (0.78-1.00) |
Abbreviations: CCP, community cancer program; CCCP, comprehensive community cancer program; INCP, integrated network cancer program.