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| Increased Risk | Zolpidem Users, % (95% CI) |
|---|---|
| Sustained use | 68.2 (62.5-73.9) |
| Higher dose | |
| Female | 68.0 (60.7-75.3) |
| Age ≥65 y | 64.0 (53.0-75.0) |
| Other CNS depressant usea | 41.4 (34.9-47.9) |
| Opioid | 26.5 (21.8-31.2) |
| Benzodiazepine | 20.3 (16.8-23.8) |
| ≥2 Safety issues | 77.4 (70.5-84.3) |
Abbreviation: CNS, central nervous system.
Sustained use; more than 1 medication possible.
