Table 3. Survival Time Analysis in the Merged Data Set That Includes Both Pancreatic Ductal Adenocarcinoma Cohorts Based on Kaplan-Meier Estimates.

Group	Patients, No.	Tumor-Associated Deaths, No.	Mean Value, Estimate (SE) [95% CI], mo	Median Value, Estimate (SE) [95% CI], mo	Log-rank P Value
rs353630 (CD44)
T/T	26	19	16.6 (2.0) [12.7-20.4]	16.0 (4.2) [7.8-24.2]	.007
C/T	123	68	37.7 (4.8) [28.3-47.1]	22.7 (1.9) [19.0-26.5]
C/C	179	110	38.6 (3.7) [31.4-45.8]	20.4 (2.2) [15.9-24.8]
C-allele	302	178	39.1 (3.1) [33.1-45.2]	21.4 (1.3) [19.0-23.9]	.002
rs684559 (CHI3L2)
A/A	48	35	17.2 (2.2) [12.9-21.5]	13.0 (1.3) [10.5-15.5]	1.00 × 10−5
A/G	154	85	43.1 (4.6) [34.2-52.1]	24.0 (3.4) [17.4-30.6]
G/G	127	78	35.1 (4.1) [27.1-43.1]	20.8 (2.3) [16.4-25.3]
G-allele	281	163	40.2 (3.2) [33.9-46.5]	23.0 (1.9) [19.3-26.7]	4.00 × 10−6
AJCC
1	19	7	46.0 (9.2) [28.0-64.0]	21.9 (NA)	.005
2	282	169	38.3 (3.1) [32.2-44.3]	22.5 (1.3) [19.9-25.1]
3	12	8	14.5 (2.0) [10.6-18.3]	17.0 (2.0) [13.0-21.0]
4	18	16	18.0 (3.4) [11.3-24.7]	15.0 (3.2) [8.8-21.2]
R status
0	207	123	42.1 (3.7) [34.70-49.4]	23.6 (3.0) [17.8-29.4]	2.00 × 10−4
1	109	65	29.0 (4.3) [20.6-37.5]	18.5 (1.7) [15.2-21.8]
2	15	12	13.9 (2.3) [9.4-18.4]	15.0 (5.0) [5.3-24.7]
Signature
Risk-indicatinga	70	51	17.0 (1.7) [13.6-20.4]	15.0 (1.5) [12.1-17.9]	2.00 × 10−8
Protectiveb	261	149	41.9 (3.4) [35.3-48.6]	24.0 (3.0) [18.1-29.9]

Abbreviations: AJCC, American Joint Commission on Cancer; NA, not applicable.

^aThe risk-indicating genotypes are the rs353630 T/T and/or rs684559 A/A genotypes.

^bThe protective genotypes are those that include an rs353630 C allele and/or rs684559 G allele.