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. 2018 Nov 26;173(1):52–59. doi: 10.1001/jamapediatrics.2018.4138

Table 2. Abnormal Fetal Brain MRI and US Cases Among ZIKV-Exposed Cohort.

Patient No. Image 1 Image 2
GA, wk Fetal MRI Fetal US GA, wk Fetal MRI Fetal US
1 18 6/7 Abnormal ventricular zone, focal cerebral migration abnormality Normal 22 3/7 Subependymal heterotopias; unexpected cortical indentation in the left parietal region Normal, slight decrease in HC percentile
2 32 1/7 Abnormal midbrain tectum, cerebellar dysplasia, lateral ventriculomegaly, thin white matter and corpus callosum, heterotopias, cortical dysplasia Mild ventriculomegaly, small cerebellum, HC 38th percentile 36 1/7 Multiple heterotopias, decreased white matter volume, beaked tectum, atrophic cerebral white matter, suspect polymicrogyria Severe ventriculomegaly, small cerebellum, HC 3.6th percentile
3 28 5/7 Chiari II malformation and parietal encephalocele Microcephaly (HC <3rd percentile), Chiari II, encephalocele 37 1/7 Microcephaly, Chiari II malformation and parietal encephalocele Microcephaly (HC <3rd percentile), Chiari II, encephalocele

Abbreviations: GA, gestational age; HC, head circumference; MRI, magnetic resonance imaging; US, ultrasonography; ZIKV, Zika virus.