Table 2. Abnormal Fetal Brain MRI and US Cases Among ZIKV-Exposed Cohort.
Patient No. | Image 1 | Image 2 | ||||
---|---|---|---|---|---|---|
GA, wk | Fetal MRI | Fetal US | GA, wk | Fetal MRI | Fetal US | |
1 | 18 6/7 | Abnormal ventricular zone, focal cerebral migration abnormality | Normal | 22 3/7 | Subependymal heterotopias; unexpected cortical indentation in the left parietal region | Normal, slight decrease in HC percentile |
2 | 32 1/7 | Abnormal midbrain tectum, cerebellar dysplasia, lateral ventriculomegaly, thin white matter and corpus callosum, heterotopias, cortical dysplasia | Mild ventriculomegaly, small cerebellum, HC 38th percentile | 36 1/7 | Multiple heterotopias, decreased white matter volume, beaked tectum, atrophic cerebral white matter, suspect polymicrogyria | Severe ventriculomegaly, small cerebellum, HC 3.6th percentile |
3 | 28 5/7 | Chiari II malformation and parietal encephalocele | Microcephaly (HC <3rd percentile), Chiari II, encephalocele | 37 1/7 | Microcephaly, Chiari II malformation and parietal encephalocele | Microcephaly (HC <3rd percentile), Chiari II, encephalocele |
Abbreviations: GA, gestational age; HC, head circumference; MRI, magnetic resonance imaging; US, ultrasonography; ZIKV, Zika virus.