Table 2. Unadjusted EDI Outcomes for Sibling Pairs, Classified by Exposure to Surgery.
| Outcome by Domain | Siblings | |||
|---|---|---|---|---|
| Concordant Pairs | Discordant Pairs | |||
| Both Surgery (n = 734) | Neither Surgery (n = 16 368) | No Surgery (n = 2346) | Surgery (n = 2346) | |
| Early developmental vulnerability, No. (%) | 154 (21.0) | 3307 (20.2) | 432 (18.4) | 543 (23.1) |
| Multiple challenge index, No. (%) | 9 (1.2) | 294 (1.8) | 35 (1.5) | 66 (2.8) |
| Language and cognitive development | ||||
| Domain score, mean (SD) | 8.93 (1.32) | 8.94 (1.43) | 8.97 (1.42) | 8.85 (1.52) |
| ≤10th Percentile, No. (%) | 33 (4.5) | 884 (5.4) | 131 (5.6) | 146 (6.2) |
| Physical health and well-being | ||||
| Domain score, mean (SD) | 8.97 (1.16) | 9.07 (1.15) | 9.06 (1.16) | 8.97 (1.20) |
| ≤10th Percentile, No. (%) | 75 (10.2) | 1571 (9.6) | 225 (9.6) | 272 (11.6) |
| Social knowledge and competence | ||||
| Domain score, mean (SD) | 8.63 (1.52) | 8.70 (1.56) | 8.75 (1.50) | 8.51 (1.66) |
| ≤10th Percentile, No. (%) | 41 (5.6) | 934 (5.7) | 123 (5.2) | 161 (6.9) |
| Emotional health and maturity | ||||
| Domain score, mean (SD) | 8.32 (1.25) | 8.35 (1.33) | 8.43 (1.29) | 8.17 (1.42) |
| ≤10th Percentile, No. (%) | 44 (6.0) | 1074 (6.6) | 147 (6.3) | 201 (8.6) |
| Communication skills and general knowledge | ||||
| Domain score, mean (SD) | 8.22 (2.13) | 8.16 (2.28) | 8.27 (2.20) | 8.10 (2.31) |
| ≤10th Percentile, No. (%) | 47 (6.4) | 1290 (7.9) | 165 (7.0) | 198 (8.4) |
Abbreviation: EDI, Early Development Instrument.