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. 2018 Nov 5;173(1):29–36. doi: 10.1001/jamapediatrics.2018.3662

Table 3. Adjusted Odds of Early Developmental Vulnerability, a Multiple Challenge Index, or Major Domains in the Lowest Tenth Percentile and Adjusted Estimates for EDI Major Domain Scores After Exposure to Surgery Before Primary School Entry.

EDI Outcome ≤10th Percentile Score
Adjusted OR (95% CI) P Value Estimate (95% CI) P Value
Overall early developmental vulnerability 1.03 (0.98 to 1.14) .58 NA NA
Multiple challenge index 1.16 (0.89 to 1.51) .27 NA NA
Major EDI domains
Language and cognitive development 0.96 (0.80 to 1.14) .61 0.00 (−0.06 to 0.05) .86
Physical health and well-beinga 1.09 (0.96 to 1.24) .19 −0.04 (−0.09 to −1.95) .05
Social knowledge and competence 0.98 (0.84 to 1.14) .83 −0.04 (−0.10 to 0.01) .13
Emotional heath and maturity 0.98 (0.84 to 1.14) .81 −0.02 (−0.07 to 0.03) .40
Communication skills and general knowledge 0.90 (0.77 to 1.05) .17 0.05 (−0.03 to 0.14) .20

Abbreviations: EDI, Early Development Instrument; NA, not applicable; OR, odds ratio.

a

Not adjusted for eldest sibling status due to lack of model convergence.