Table 1. Indicators of Depression and Age-Standardized Demographic and Health Characteristics by History of Depression Among 187 441 Women Participating in the NHS (1996) and NHS II (1997).
Indicator or Characteristic | Women, %a | |
---|---|---|
Without History of Depression (n = 140 654) | With History of Depressionb (n = 46 787) | |
Indicator of depression | ||
Depression diagnosis only | 0 | 3.6 |
Depressive symptoms only (MHI-5 score <60) | 0 | 48.9 |
Antidepressant use only | 0 | 23.9 |
Depression diagnosis and depressive symptoms | 0 | 1.4 |
Depression diagnosis and antidepressant use | 0 | 2.8 |
Depressive symptoms and antidepressant use | 0 | 17.1 |
Depression diagnosis, depressive symptoms, and antidepressant use | 0 | 2.3 |
Demographic and health factor | ||
Age, mean (SD), y | 52.3 (11.7) | 48.5 (10.1) |
Nonwhite | 7.4 | 6.4 |
Menarche before age 10 y | 6.6 | 7.5 |
BMI, mean (SD) | 26.1 (5.5) | 27.0 (6.2) |
Income <$60 000 | 49.3 | 51.5 |
Oral contraceptive use ever | 69.2 | 72.5 |
Exercise ≥10 metabolic equivalents/wk | 48.2 | 43.1 |
Alcohol consumption | ||
None | 24.2 | 24.4 |
>0 and <5 g/d | 47.1 | 47.9 |
≥5 g/d | 25.7 | 25.6 |
Smoking | ||
Never | 56.9 | 50.7 |
Past | 32.6 | 34.9 |
Current | 10.5 | 14.4 |
Menopause and hormone use | ||
Premenopausal | 47.4 | 45.6 |
Postmenopausal and no hormone use | 15.3 | 12.7 |
Postmenopausal and hormone use | 33.3 | 38.7 |
Region of residency | ||
Northeast | 42.3 | 40.0 |
Midwest | 25.6 | 26.4 |
South | 17.7 | 19.2 |
West | 14.4 | 14.5 |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); MHI-5, 5-item Mental Health Inventory; NHS, Nurses’ Health Study.
Values are standardized to the age distribution of the study population. Values of polytomous variables may not sum to 100% owing to rounding.
Women were considered to have a history of depression if, by 1996 or 1997, they had reported regular antidepressant use, received a diagnosis of depression, or had an MHI-5 score of less than 60.