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. 2018 Sep 12;75(12):1225–1233. doi: 10.1001/jamapsychiatry.2018.2462

Table 1. Indicators of Depression and Age-Standardized Demographic and Health Characteristics by History of Depression Among 187 441 Women Participating in the NHS (1996) and NHS II (1997).

Indicator or Characteristic Women, %a
Without History of Depression (n = 140 654) With History of Depressionb (n = 46 787)
Indicator of depression
Depression diagnosis only 0 3.6
Depressive symptoms only (MHI-5 score <60) 0 48.9
Antidepressant use only 0 23.9
Depression diagnosis and depressive symptoms 0 1.4
Depression diagnosis and antidepressant use 0 2.8
Depressive symptoms and antidepressant use 0 17.1
Depression diagnosis, depressive symptoms, and antidepressant use 0 2.3
Demographic and health factor
Age, mean (SD), y 52.3 (11.7) 48.5 (10.1)
Nonwhite 7.4 6.4
Menarche before age 10 y 6.6 7.5
BMI, mean (SD) 26.1 (5.5) 27.0 (6.2)
Income <$60 000 49.3 51.5
Oral contraceptive use ever 69.2 72.5
Exercise ≥10 metabolic equivalents/wk 48.2 43.1
Alcohol consumption
None 24.2 24.4
>0 and <5 g/d 47.1 47.9
≥5 g/d 25.7 25.6
Smoking
Never 56.9 50.7
Past 32.6 34.9
Current 10.5 14.4
Menopause and hormone use
Premenopausal 47.4 45.6
Postmenopausal and no hormone use 15.3 12.7
Postmenopausal and hormone use 33.3 38.7
Region of residency
Northeast 42.3 40.0
Midwest 25.6 26.4
South 17.7 19.2
West 14.4 14.5

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); MHI-5, 5-item Mental Health Inventory; NHS, Nurses’ Health Study.

a

Values are standardized to the age distribution of the study population. Values of polytomous variables may not sum to 100% owing to rounding.

b

Women were considered to have a history of depression if, by 1996 or 1997, they had reported regular antidepressant use, received a diagnosis of depression, or had an MHI-5 score of less than 60.