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. 2018 Oct 31;3(11):1070–1078. doi: 10.1001/jamacardio.2018.3562

Table 1. Characteristics of Patients Undergoing TAVR Procedures by Hospital SAVR Volume.

Characteristic Patients, No. (%) P Value All Patients, No. (%) (N = 60 538)
Low SAVR (n = 29 454) High SAVR (n = 31 084)
Age, mean (SD), y 82.1 (8.0) 82.5 (8.1) <.001 82.3 (8.0)
Female sex 14 167 (48.1) 15 006 (48.3) .66 29 173 (48.2)
White race 27 130/29354 (92.4) 29 071/30999 (93.8) <.001 56 201/60353 (93.1)
Comorbidities within 1 y
Coronary artery disease 23 379 (79.4) 24 848 (79.9) .09 48 227 (79.7)
Hypertension 27 130 (92.1) 28 729 (92.4) .15 55 859 (92.3)
Chronic heart failure 23 224 (78.9) 25 485 (82.0) <.001 48 709 (80.5)
Diabetes 11 969 (40.6) 12 323 (39.6) .01 24 292 (40.1)
Chronic pulmonary disease 11 780 (40.0) 12 461 (40.1) .81 24 241 (40.0)
Obesity 5738 (19.5) 5896 (19.0) .11 11 634 (19.2)
Cerebrovascular disease 2394 (8.1) 2614 (8.4) .21 5008 (8.3)
Peripheral artery disease 8313 (28.2) 8879 (28.6) .35 17 192 (28.4)
Recent conditions within 90 d
Cardiovascular eventsa 4655 (15.8) 4790 (15.4) .18 9445 (15.6)
Atrial fibrillation or flutter 12 262 (41.6) 13 553 (43.6) <.001 25 815 (42.6)
Renal failure 2830 (9.6) 3202 (10.3) .004 6032 (10.0)
Previous valve intervention 3543 (12.0) 3936 (12.7) .02 7479 (12.4)
Previous CABG or septal defect repair 3524 (12.0) 3748 (12.1) .72 7272 (12.0)
Previous PCI 6588 (22.4) 6889 (22.2) .54 13 477 (22.3)
Approach of procedure <.001
Transfemoral 24 804 (84.2) 27 157 (87.4) 51 961 (85.8)
Transapical 4650 (15.8) 3927 (12.6) 8577 (14.2)
Elective procedure 23 771 (80.7) 23 430 (75.4) <.001 47 201 (78.0)
Concurrent PCI 1004 (3.4) 1047 (3.4) .78 2051 (3.4)
Teaching hospital 13 313 (45.2) 23 386 (75.2) <.001 36 699 (60.6)
Hospital region <.001
Northeast 4908 (16.7) 11 187 (36.0) 16 095 (26.6)
Midwest 6617 (22.4) 7352 (23.6) 13 969 (23.1)
South 11 521 (39.1) 8145 (26.2) 19 666 (32.5)
West 6408 (21.8) 4400 (14.2) 10 808 (17.9)
Hospital TAVR volume (all years) <.001
Low 21 113 (71.7) 10 703 (34.4) 31 816 (52.6)
High 8341 (28.3) 20 381 (65.6) 28 722 (47.4)
Hospital PCI volume <.001
Low 19 977 (67.8) 10 258 (33.0) 30 235 (49.9)
High 9477 (32.2) 20 826 (67.0) 30 303 (50.1)

Abbreviations: CABG, coronary artery bypass graft; PCI, percutaneous coronary intervention; SAVR, surgical aortic valve replacement; TAVR, transcatheter aortic valve replacement.

a

Recent cardiovascular conditions included acute myocardial infarction, carotid stenosis, and endocarditis.