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Summary of lipid-linked oligosaccharide synthesis in a Wzy-dependent manner. Lipid-linked oligosaccharides are first assembled at the cytoplasmic leaflet of the inner-membrane, flipped to the periplasm, and polymerized by a Wzy polymerase where they then can be transferred by WaaL ligases or OTases to the outer core saccharide of LPS or proteins, respectively.
