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. Author manuscript; available in PMC: 2020 Jan 23.
Published in final edited form as: J Am Chem Soc. 2019 Jan 11;141(3):1312–1323. doi: 10.1021/jacs.8b11477

Figure 2.

Figure 2.

Aglaroxin C (6) and analogues (121 and 12s) neither inhibit HCV RNA replication nor protein translation. HCV replicon cell line 2-3+ was treated with indicated compounds for 3 h. Cells were incubated for an additional 48 (A & C) or 72 h (B & D). Cellular RNA or protein was isolated for quantifications of HCV viral RNA by real-time PCR (A & B) or non-structural protein NS5 by western blotting (C & D).