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. Author manuscript; available in PMC: 2019 Jun 19.
Published in final edited form as: EMBnet J. 2019 May 22;24:e921. doi: 10.14806/ej.24.0.921

Figure 2.

Figure 2.

3D molecular modelling studies on point mutations of Notch 3 indicates a significant loss of 3D structure, thus resulting in a partially unfolded protein with compromised functionality. The study was performed in the Molecular Operating Environment (MOE 2011.10). Montreal, Quebec, Canada: Chemical Computing Group ULC2