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. 2019 Apr 4;5(7):1028–1035. doi: 10.1001/jamaoncol.2019.0086

Table 2. Top 10 Complications of Systemic Therapy or Radiotherapy With Associated Admission, Mortality Rates, and Charges, 2006-2015.

Diagnosis Visits, No. (%) Rate, % Total Charges (Billions), $
Admission Mortality
Neutropenia 136 167 (8.9) 94.6 1.9 5.52
Sepsis 128 171 (8.4) 99.4 17.0 11.21
Anemia 117 557 (7.7) 91.7 3.6 6.78
Pneumonia 80 451 (5.3) 98.8 7.7 5.11
Nausea and vomiting 58 077 (3.8) 66.9 0.6 1.02
Dehydration 52 012 (3.4) 86.9 2.5 1.44
Acute kidney injury 47 830 (3.1) 99.0 8.1 3.10
Intestinal obstruction (without hernia) 34 078 (2.2) 97.9 2.9 1.88
Gastrointestinal tract hemorrhage 24 265 (1.6) 93.4 3.9 1.01
Congestive heart failure 23 718 (1.6) 97.8 4.2 1.15