Table 2. Univariate and Multivariate Logistic Regression Analyses of Potential Risk Factors and the Association With Loss to Follow-up Among Patients With Neovascular Age-Related Macular Degeneration Who Received Intravitreal Anti–Vascular Endothelial Growth Factor Injections.

Variable	Lost to Follow-up, No. (%)	Univariate Model		Multivariate Modela
		Odds Ratio (95% CI)	P Value	Odds Ratio (95% CI)	P Value
Age, y
≤80	583 (15.8)	1 [Reference]		1 [Reference]
81-85	458 (21.1)	1.42 (1.24-1.63)	<.001	1.58 (1.38-1.82)	<.001
86-90	567 (27.8)	2.05 (1.80-2.33)	<.001	2.29 (2.00-2.62)	<.001
>90	395 (35.7)	2.95 (2.54-3.44)	<.001	3.31 (2.83-3.86)	<.001
Sex
Male	679 (22.0)	1 [Reference]
Female	1324 (22.4)	1.02 (0.92-1.14)	.66	ND	ND
Race/ethnicity
White	1606 (20.3)	1 [Reference]		1 [Reference]
African American	39 (27.3)	1.47 (1.01-2.13)	.04	1.47 (1.00-2.16)	.05
Asian	34 (33.7)	1.99 (1.31-3.02)	.001	2.63 (1.71-4.03)	<.001
Otherb	11 (42.3)	2.88 (1.32-6.27)	.008	3.07 (1.38-6.82)	.006
Unreported	313 (37.6)	2.37 (2.04-2.75)	<.001	2.29 (1.96-2.68)	<.001
Regional average AGI, $
>100 000	362 (18.4)	1 [Reference]		1 [Reference]
76 000-100 000	392 (21.7)	1.23 (1.05-1.44)	.01	1.28 (1.08-1.50)	.004
51 000-75 000	765 (22.8)	1.32 (1.14-1.51)	<.001	1.35 (1.17-1.56)	<.001
≤50 000	484 (25.8)	1.55 (1.33-1.81)	<.001	1.52 (1.30-1.79)	<.001
Distance, miles
≤10	1355 (21.7)	1 [Reference]		1 [Reference]
11-20	374 (21.6)	1.00 (0.88-1.14)	.97	1.05 (0.91-1.20)	.51
21-30	103 (25.1)	1.21 (0.96-1.53)	.10	1.33 (1.05-1.69)	.02
>30	171 (27.5)	1.37 (1.14-1.65)	.001	1.55 (1.28-1.88)	<.001
Eye involvement
Bilateral	518 (18.0)	1 [Reference]		1 [Reference]
Unilateral	1485 (24.2)	1.45 (1.30-1.62)	<.001	1.44 (1.28-1.61)	<.001

Abbreviation: AGI, adjusted gross income (rounded to the nearest $1000); ND, no data.

^aMultivariate analysis adjusted for age, race/ethnicity, regional average AGI, distance, and eye involvement.

^bOther includes Hispanic, Native American, and Pacific Islander.