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. 2019 Mar 27;76(8):826–833. doi: 10.1001/jamapsychiatry.2019.0248

Table 2. Lifetime Suicide Attempts Among Relatives by Lifetime Mental Disorders, Number of Disorders, and Global Severity.

Lifetime Disorder Lifetime Suicide Attempts Odds Ratio (95% CI)a Adjusted Odds Ratio (95% CI)b
Yes (n = 199) No (n = 5156)
Mood, No. (%)
Bipolar I 48 (24.7) 94 (1.8) 16.2 (10.4-25.1) 36.1 (21.0-61.9)
Bipolar II 8 (4.1) 77 (1.5) 2.0 (0.9-4.5) 7.1 (3.0-16.8)
Major depression 98 (50.0) 1069 (21.0) 3.2 (2.3-4.3) 6.4 (4.3-9.4)
Anxiety, No. (%)
Panic 26 (13.4) 150 (2.9) 3.7 (2.3-6.0) 1.4 (0.8-2.3)
Generalized anxiety 50 (25.5) 356 (6.9) 4.0 (2.7-6.0) 1.5 (0.9-2.3)
Social anxiety 31 (15.7) 288 (5.6) 2.5 (1.6-3.8) 1.0 (0.6-1.6)
Substance, No. (%)
Substance use 59 (30.6) 583 (11.4) 3.6 (2.5-5.0) 2.0 (1.4-3.0)
No. of disorders, No. (%)
0 23 (11.6) 3114 (60.4)c NA NA
1 63 (31.7) 1150 (22.3) NA NA
2 62 (31.2) 636 (12.3) NA NA
≥3 51 (25.6) 255 (5.0) NA NA
Global functioning, mean
Lifetime 54.1 73.4c NA NA
Current 38.4 70.5c NA NA
Worst 25.7 59.0c NA NA

Abbreviation: NA, not applicable.

a

Unadjusted.

b

Adjusted for other disorders.

c

P < .001.