Table 1. General Characteristics of Patients.
Characteristic | Overall Cohort (N = 193) |
---|---|
Age, mean (SD), y | 64 (11) |
BMI, median (IQR) | 24.0 (21.5-27.0) |
<25 | 131 (67.9) |
≥25 | 62 (32.1) |
Sarcopenia, No. (%) | 84 (43.5) |
Sex, No. (%) | |
Male | 97 (50.3) |
Female | 96 (49.7) |
Stage at diagnosis, No. (%) | |
Borderline resectable | 63 (32.6) |
Locally advanced | 130 (67.4) |
NT scheme, No. (%) | |
FOLFIRINOX | 124 (64.2) |
PAXG/PEXG | 54 (28.0) |
Gemcitabine based | 15 (7.8) |
Tumor size, mean (SD), mm | |
Pre-NT | 33.4 (13.4) |
Post-NT | 25.8 (13.51) |
Radiologic response, No. (%) | |
Stable disease | 127 (65.8) |
Partial or complete | 51 (26.4) |
Progressive disease | 15 (7.8) |
Months from diagnosis to surgery, median (IQR) | 6 (4-7) |
Resection, No. (%) | |
No. | 57 (29.5) |
Yes | 136 (70.5) |
Vascular resection, No. (%) | 19 (14.0) |
Category at pathologic examination, No. (%) | |
Tx | 7 (5.1) |
T1-T2 | 25 (18.4) |
T3 | 100 (73.5) |
T4 | 4 (2.9) |
Nodal involvement, No. (%) | |
N0 | 82 (60.3) |
N1 | 54 (39.7) |
Negative resection margins (R0), No. (%) | 92 (67.6) |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); FOLFIRINOX, combined fluorouracil, irinotecan, oxaliplatin, leucovorin, and folic acid; PEXG, combined cisplatin, epirubicin, capecitabine, and gemcitabine; IQR, interquartile range; NT, neoadjuvant treatment; PAXG, combined cisplatin, capecitabine, gemcitabine, and nanoparticle albumin–bound paclitaxel.