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. Author manuscript; available in PMC: 2019 Jun 19.
Published in final edited form as: Nat Struct Mol Biol. 2018 Sep 6;25(9):754–765. doi: 10.1038/s41594-018-0122-9

Figure 1. Structure of mitochondrial RNA polymerase (mtRNAP).

Figure 1

Ribbon depiction of human mitochondrial RNA polymerase (PDB ID: 3SPA) colored according to domains: PPR domain: deepteal; N-terminal domain: grey; Palm: green; Fingers: pink; intercalating hairpin: purple, Thumb: orange. Important structural elements are indicated. Below is a schematic depiction of mtRNAP and T7 RNAP domains and important structural elements. Structurally homologous regions between mtRNAP and T7 RNAP are aligned.