Table 2.

Incidence of TRC105-Related Adverse Events (n = 13)

Adverse Event	All Grades	Grade 1	Grade 2	Grade 3	Grade 4
Anemia	6 (46)	1 (8)	4 (31)	1 (8)	–
Anorexia	1 (8)	1 (8)	–	–	–
Cough	1 (8)	1 (8)	–	–	–
Edema (Limbs)	1 (8)	1 (8)	–	–	–
Epistaxis	6 (46)	6 (46)	–	–	–
Fatigue	1 (8)	1 (8)	–	–	–
Gum Bleeding	4 (31)	4 (31)	–	–	–
Headache	9 (69)	8 (62)	1 (8)	–	–
Hematuria	1 (8)	1 (8)	1 (8)	–	–
Hypoalbuminemia	1 (8)	1 (8)	–	–	–
Hypophosphatemia	1 (8)		1 (8)	–	–
Increased Alanine Aminotransferase	1 (8)	1 (8)	–	–	–
Infusion-Related Reaction	9 (69)	5 (38)	4 (31)	–	–
Maculopapular Rash	1 (8)	1 (8)	–	–	–
Nasal Congestion	3 (23)	3 (23)	–	–	–
Nausea	1 (8)	1 (8)	–	–	–
Proteinuria	1 (8)	1 (8)	–	–	–
Skin Infection	1 (8)	–	–	1 (8)	–
Telangiectasia	6 (46)	6 (46)	–	–	–
Vomiting	1 (8)	1 (8)	–	–	–
Xerostomia	1 (8)	1 (8)	–	–	–