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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: J Mol Med (Berl). 2019 May 17;97(7):1033–1047. doi: 10.1007/s00109-019-01791-z

Figure 4.

Figure 4.

In vivo characterization of D166V HCM (A) and WT (B) ~1-month post AAV/PBS systemic delivery. Abbreviations: HW/BW, Heart Weight to Body Weight ratio; LVAW;d, left ventricular anterior wall in diastole; LVID;d, left ventricular (LV) inner diameter in diastole; LVPW;s, LV posterior thickness in systole; Cardiac Output; EDV, end-diastolic volume; Tau, Relaxation constant; PRSW, Preload recruitable stroke work; dP/dtmax-EDV, peak rate of rise in LV pressure-end diastolic volume relationship. C. MPI, myocardial performance index for D166V and WT mice ~l-month post AAV/PBS delivery. Data are mean ± SEM. *P<0.05, **P<0.01, and ***P<0.001, by Student’s t-test.